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Identifying Critical Parameters in SIR Model for Spread of Disease  [PDF]
Sarbaz H. A. Khoshnaw, Najem A. Mohammad, Rizgar H. Salih
Open Journal of Modelling and Simulation (OJMSi) , 2017, DOI: 10.4236/ojmsi.2017.51003
Abstract: Calculating analytical approximate solutions for non-linear infectious disease models is a difficult task. Such models often require computational tools to analyse analytical approximate methods which appear in some theoretical and practical applications in systems biology. They represent key critical elements and give some approximate solutions for such systems. The SIR epidemic disease model is given as the non-linear system of ODE’s. Then, we use a proper scaling to reduce the number of parameters. We suggest Elzaki transform method to find analytical approximate solutions for the simplified model. The technique plays an important role in calculating the analytical approximate solutions. The local and global dynamics of the model are also studied. An investigation of the behaviour at infinity was conducted via finding the lines and singular points at infinity. Model dynamic results are computed in numerical simulations using Pplane8 and SimBiology Toolbox for Mathlab. Results provide a good step forward for describing the model dynamics. More interestingly, the simplified model could be accurate, robust, and used by biologists for different purposes such as identifying critical model elements.
Metastatic Renal Cell Carcinoma in an Ovarian Benign Mixed Mucinous Cystadenoma and Brenner Tumour: A Case Report
Amar Ibrahim,Mohammad Salih Al-Jafari
Case Reports in Pathology , 2012, DOI: 10.1155/2012/523231
Abstract: This is a case of a 71-year-old woman, who presented with a large abdominal mass. Microscopic examination revealed metastatic renal cell carcinoma in an otherwise massively enlarged benign ovarian tumour of mixed mucinous cystadenoma and Brenner tumour. Clinicopathological and radiological assessment together with a thorough evaluation of gross and histological features, including the use of immunohistochemical stains, is essential to confirm the diagnosis and rule out the possibility of primary clear cell carcinoma of ovary, as this has important prognostic and therapeutic implications.
Metastatic Renal Cell Carcinoma in an Ovarian Benign Mixed Mucinous Cystadenoma and Brenner Tumour: A Case Report
Amar Ibrahim,Mohammad Salih Al-Jafari
Case Reports in Pathology , 2012, DOI: 10.1155/2012/523231
Abstract: This is a case of a 71-year-old woman, who presented with a large abdominal mass. Microscopic examination revealed metastatic renal cell carcinoma in an otherwise massively enlarged benign ovarian tumour of mixed mucinous cystadenoma and Brenner tumour. Clinicopathological and radiological assessment together with a thorough evaluation of gross and histological features, including the use of immunohistochemical stains, is essential to confirm the diagnosis and rule out the possibility of primary clear cell carcinoma of ovary, as this has important prognostic and therapeutic implications. 1. Introduction Renal cell carcinoma (RCC) is the most common malignant tumour of the kidney. It constitutes 75% of renal neoplasms in adults and 3% of all adult malignancies [1]. Approximately 30% of patients present with distant metastasis at the time of diagnosis [1, 2]. Metastatic renal cell carcinoma to the ovary is uncommon, and so far only small number of cases has been reported in the literature [3]. Furthermore, the presence of metastatic renal cell carcinoma in an existing benign mixed mucinous cystadenoma and Brenner tumor is an extremely rare occurrence. 2. Case Presentation A 71-year-old woman presented clinically with abdominal distention and weight loss. On physical examination, the patient had a large abdominal mass. Blood biochemistry showed Urea 6.5?mmol/L, Creatinine 77?umol/L, Sodium: 136?mmol/L, Potassium 5.2?mmol/L, and GFR 79?mL/min/1.7?m2. The tumour markers showed CA125 was 7.4?KU/L (normal ≤ 35), CA19.9 = 19?KU/L (normal ≤ 35), and CEA = 1.2?μg/L (normal ≤ 4). The abdominal/pelvic ultrasound revealed a right ovarian mass which was confirmed on CT scan. Laparotomy was performed, and the ovarian mass together with right fallopian tube were excised. The mass weighed 9.5?kg and measured 290 × 115 × 120?mm. Sectioning of the mass showed a multilocular cystic areas containing amber coloured, thick mucoid material alternating with multiple, solid firm nodules within the fibrous stroma of the walls. Histological examination showed a multilocular cystic ovarian tumour which consisted of mixed benign mucinous cystadenoma and Brenner tumour (Figures 1 and 2). This mixed tumour forms the main component of the cystic mass. In addition, there were densely packed glandular structures lined by clear cells arranged in nests separated by vascular stroma. The nuclei are small, uniform with minimal pleomorphism and no prominent nucleoli or discernible mitoses (Figures 3 and 4). Figure 1: Part of the tumour showing benign mucinous cystadenoma. Figure 2: Part of the
Analytical Evaluation of Energy and Electron Concentrations in Quantum Wells of the High Electron Mobility Transistors  [PDF]
Salih Saygi
Open Journal of Applied Sciences (OJAppS) , 2014, DOI: 10.4236/ojapps.2014.43014
Abstract: In this letter we propose analytical evaluation method for the electron density and the energy density in multi-layered high electron mobility transistors (HEMTs). The algorithm is used to simulate the variation of the electron density and the energy density against temperature of hetero-junction AlGaN/GaN. The proposed procedure guaranties the reliable application of the contribution of multi-layered HEMTs structure. In conclusion, the obtained results are estimated and discussed.
Predictors of gastrointestinal lesions on endoscopy in iron deficiency anemia without gastrointestinal symptoms
Shahid Majid, Mohammad Salih, Rozina Wasaya, Wasim Jafri
BMC Gastroenterology , 2008, DOI: 10.1186/1471-230x-8-52
Abstract: Ninety five consecutive patients with laboratory based diagnosis of IDA having no gastrointestinal symptoms were interviewed and their clinical and biochemical variables were recorded. All the study patients underwent esophago-gastroduodenoscopy (EGD) and colonoscopy. Endoscopic findings were documented as presence/absence of bleeding related lesion and presence/absence of cause of IDA. Multiple logistic regressions were performed to identify variables significantly related to outcome variables.Possible cause of anaemia was found in 71% and bleeding related lesions were found in 53% of patients. Upper gastrointestinal tract lesions were found in 41% of patients with bleeding related lesions. On multivariable logistic regression; advancing age, low mean corpuscular volume (MCV ≤ 60 fl), and positive fecal occult blood test were predictive factors for bleeding related GI lesions and cause of IDAClinical and Biochemical markers can predict gastrointestinal lesions on endoscopy in IDA patients without gastrointestinal symptoms. High proportion of upper gastrointestinal involvement warrants EGD as initial endoscopic procedure however, this needs validation by further studies.Anaemia is common among general population in developing Asian countries. Iron deficiency is a common cause of anaemia either due to poor intake or chronic blood loss. Iron deficiency anaemia is usually due to chronic gastrointestinal (GI) blood loss when there is no obvious source of bleeding. The standard of care for these patients with IDA includes evaluation of the Gastrointestinal (GI) tract for bleeding lesions [1].Iron deficiency anemia is considered as an alarm sign for the presence of possible GI malignancies, and inadequate evaluation of patients with IDA may delay the diagnosis of GI tumors especially colorectal cancer [2]. In 20% of patients with IDA a routine upper and lower GI endoscopy may not ascertain GI cause during hospital admission [3].The available literature, in heterogeneous g
Differentiating Asthma from its mimics
Zeeshan Waheed,Muhammad Irfan,Mohammad Salih,Ali Bin Sarwar Zubairi
Chest Disease Reports , 2011, DOI: 10.4081/cdr.2011.e17
Abstract: All that wheezes is not asthma this adage accredited to Chevalier Jackson emphasizes the importance of differentiating asthma from its mimics, particularly if the patient is not responding to usual therapy. The above statement also warrants further diagnostic evaluation and management of non-asthma conditions that mimic asthma. We present here a case of a middle aged female who presented with severe bronchospasm, initially labeled as asthma but was resistant to usual anti-asthma therapy. After further workup she was eventually diagnosed to have esophageal achalasia.
Irritable Bowel Syndrome and Psychiatric Disorders in Pakistan: A Case Control Study
Amna Subhan Butt,Mohammad Salih,Wasim Jafri,Javed Yakoob,Mohammad Wasay,Saeed Hamid
Gastroenterology Research and Practice , 2012, DOI: 10.1155/2012/291452
Abstract: Background. The psychiatric disorders like anxiety and depression could have a profound influence on onset, expression, and course of Irritable bowel syndrome (IBS). Aim. To estimate the frequency and strength of association of common mental disorders (CMDs) in patients with IBS and patients with other chronic diseases, that is, migraine and hypertension. Method. This was a case control study. Individuals aged 18–70 years diagnosed as IBS were enrolled as cases. The control groups consisted of patients without IBS but diagnosed to have a chronic disease, that is, migraine or HTN. Self-Reporting Questonnaire-20(SRQ-20) was used as a screening tool for the detection of CMD. Results. 82 patients were enrolled in each group. Mean SRQ score was significantly higher in IBS group than controls (9.9±4.5 versus 4.9±3.6, <0.001). CMDs were more frequent (67.1% versus 22%) and the odds of CMD were 7.24 times higher among IBS patients than controls (95% CI 3.6–14.5, <0.001). No difference was found in frequency of CMDs among various subtypes of IBS. Conclusion. We found that CMDs are more common and strongly associated with IBS as compared to other chronic diseases. Early screening for CMDs might be useful for an effective management of IBS.
CT Optimization for Diagnosis of Some Acute Abdomen Cases  [PDF]
Saddig D. Jastaniah, Alamin M. Salih, Khalid Gh. Alsafi, Hamad Elniel H. Eltyib, Sarah Hagi, Maway A. Khafaji, Hanan Y. Abbas, Mohammad Alshihri
Advances in Computed Tomography (ACT) , 2015, DOI: 10.4236/act.2015.42003
Abstract:
The acute abdomen is one of the most frequent causes for presentation to the emergency department. Imaging plays an important role for an accurate diagnosis, which in turn diminishes morbidity and mortality. The aim of this study was to demonstrate optimum CT aspects and emphasize on the important features of CT for those patients presenting with an acute abdominal pain at the Emergency Department both in general and in a number of selected conditions (appendicitis, small-bowel obstruction, acute pancreatitis, and diverticulitis). The reported data by this study are based on the author working experience, which forms a continuous protocol adjustment process. The present study provides evidence that CT would result in definite diagnosis of patients with abdominal pain in terms of the detection of some urgent conditions.
Geochemistry of Termite Hills as a Tool for Geochemical Exploration of Glass Sand in the Iraqi Western Desert  [PDF]
Salih Muhammad Awadh
International Journal of Geosciences (IJG) , 2010, DOI: 10.4236/ijg.2010.13017
Abstract: Sand glass deposits was located in the mid of the Western Desert of Iraq. It is situated within Rutba Formation (Ceno-manian). Ancient traditional mining method is still used in exploitation the unconsolidated white glass sand from glass sand quarry. The overburden thickness ranges from 2 to 4 m in average. Termite hills were observed around the glass sand quarry extending far from the quarry area. Termites could burrows down and penetrate the sand glass bringing it up to the surface. The depth of penetration reaches more than 35 m. The field observation of the white color of termite hills which are built up by sand glass gave a good indicator for the hidden subsurface deposit and it appears to be a surface signature for finding glass sand directly under the termite hills. The scattered white hills of glass sand on the surface with high content of SiO2, concordant Zr/Hf and Th/U ratios and heavy mineral distribution in both of quarry and termite hills provide a strong evidence of that those termite hills could be an effective tool for exploring subsurface hidden glass sand up to 35 m depth.
Classification with binary gene expressions  [PDF]
Salih Tuna, Mahesan Niranjan
Journal of Biomedical Science and Engineering (JBiSE) , 2009, DOI: 10.4236/jbise.2009.26056
Abstract: Microarray gene expression measurements are reported, used and archived usually to high numerical precision. However, properties of mRNA molecules, such as their low stability and availability in small copy numbers, and the fact that measurements correspond to a population of cells, rather than a single cell, makes high precision meaningless. Recent work shows that reducing measurement precision leads to very little loss of information, right down to binary levels. In this paper we show how properties of binary spaces can be useful in making inferences from microarray data. In particular, we use the Tanimoto similarity metric for binary vectors, which has been used effectively in the Chemoinformatics literature for retrieving chemical compounds with certain functional properties. This measure, when incorporated in a kernel framework, helps recover any information lost by quantization. By implementing a spectral clustering framework, we further show that a second reason for high performance from the Tanimoto metric can be traced back to a hitherto unnoticed systematic variability in array data: Probe level uncertainties are systematically lower for arrays with large numbers of expressed genes. While we offer no molecular level explanation for this systematic variability, that it could be exploited in a suitable similarity metric is a useful observation in itself. We further show preliminary results that working with binary data considerably reduces variability in the results across choice of algorithms in the preprocessing stages of microarray analysis.
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